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Mikey’s back and about to face his greatest challenge… his new sister.
Mollie and James are together and raising a family, which now consists of an older Mikey and his baby sister, Julie. Tension between the siblings arises, and as well with Mollie and James when Mollie's brother Stuart moves in. Mikey is also learning how to use the toilet for the first time.
$12,000,000
$120,889,074
December 14, 1990
TriStar Pictures, Big Mouth Productions
38 people

John Travolta
James
Acting

Kirstie Alley
Mollie
Acting

Olympia Dukakis
Rosie
Acting

Elias Koteas
Stuart
Acting

Twink Caplan
Rona
Acting

Bruce Willis
Mikey (voice)
Acting

Roseanne Barr
Julie (voice)
Acting

Damon Wayans
Eddie (voice)
Acting

Gilbert Gottfried
Joey
Acting

Mel Brooks
Mr. Toilet Man (voice)
Acting
Lorne Sussman
Mikey
Acting
Megan Milner
Julie (1 year)
Acting

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