
Karen Best has a big life. She's a big girl with a big personality and a big love of Chardonnay, which occasionally, causes her to make some big mistakes with men. But the biggest thing about Karen is her big heart, a heart she uses to excel at her job as a counselor at a group home for young adults with Down syndrome located in an old brownstone in New York City.
November 9, 2017
1
1
Amazon Studios
5 people

Bridget Everett
Karen Best
Acting

Karen Pittman
Raquel
Acting

Loni Anderson
Jean
Acting
Luke Zimmerman
Andy
Acting

Joshua Eber
Jerry
Acting
No episodes available for this season.

2012

2010

2009

1992

2002

2022

1997

2021

2019

2023

1999

2025

2013

2014

2017

2021

2016

2009

2014

2025